Research Activities

One of the major strengths of Evaluation Software Development (ESD) and the Computer-based Health Evaluation System (CHES) solutions are their tight connection to scientific research and users in daily clinical routine. From the very beginning, the mutual interdependence of software development and use in scientific projects promoted creating a reliable, powerful and flexible tool as well as establishing comprehensive and sound scientific knowledge.

This broad high quality scientific knowledge forms the basis for services like scientific consultation regarding e.g. study design, choice of patient-reported outcome measurements (questionnaires), timing and frequency of assessments, data analysis and interpretation, evaluation of concepts of medical treatment, etc.

The following list provides references to selected research articles by collaborators of Evaluation Software Development (ESD) containing information on the development process, the adaptation, improvements and the use of the Computer-based Health Evaluation System (CHES).











2013 – 2009


  • Life vest and quality of life
  • Occupational stress and life style modification in cardiac patient
  • CHES.Cardio – computerized psychological interventions for coronary heart disease
  • Mental health interventions in cardiac patients


  • CHES.Commnity – eHealth tool for community members within the project healthy community


  • Standardized collection of disease-specific quality of life and psychosocial stress in patients with epilepsy
  • Strokecard – eHealth tool for stroke patients to manage their health data.


  • Electronic assessment of patient-reported outcomes in patients after total hip and knee arthroplasty
  • Computer-adaptive assessment of patients’ joint awareness after surgery of the hip, knee or shoulder


  • GIMEMA multicentre study – Italien Group for Adult Hematologic Diseases – An international research study.
  • EORTC BRR16/24 field study – An international research study.
  • Development of an interactive questionnaire for measuring health related quality of life – An international phase IV research study.
  • Development of an EORTC module specific for testicular cancer (EORTC QLQ-TC26): Phase IV field study including evaluation of multi-centre electronic PRO data collection with CHES
  • Making the EORTC QLQ-C30 interactive: Development of computerized adaptive testing (CAT) for EORTC QLQ-C30 dimensions
  • Development of a reference data base for self-reported physical and psychosocial symptom burden in cancer patients
  • Development of a tool for the computer-adaptive assessment of patient-reported outcomes (PRO) and its implementation in oncological care and research
  • Brief psychooncological intervention for parents of adolescents and young adults with hematologic malignancies
  • Computerized monitoring of patient-reported adverse events and health status (CoMPAHS)
  • Development of Health Policy Recommendations for a Personalized Cervical Cancer Screening Program
  • CML Registry and CML Outcome & Policy Model -Extension, further Development and Application
  • Development of a Personalized Decision Tool for Potential Prostate Cancer Screening Candidates and their Physicians
  • AMR 2.0 (Austrian Myeloma Registry)
  • Telemonitoring of somatic and psychosocial symptoms and side effects in oncological patients (ONCO-TEL)
  • Comprehensive evaluation study of chemotherapy effectiveness with focus quality of life in patients with metastatic colorectal cancer
  • Optimization of psychooncological support in medical care/ Stepped Care
  • Evaluation of health related quality of life during pemetrexed (Alimta®) consolidation therapy in patients with advanced non-small cell lung cancer (NSCLC)
  • Phase III and Phase IV module development studies
  • Platform for self-help strategies
  • Patient information portals